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Noella Lopes, PhD
We used the SCENITH kit and this allowed us to demonstrate the metabolic dichotomy between gamma delta T cell subsets in the thymus, periphery but also in the tumor microenvironment *1. The kit is easy to use and very useful to study the metabolic profile of cells in rare cell populations. We obtained very rapidly and in a simple way a large amount of information about metabolism like glycolytic capacity, glucose/mitochondria dependency, fatty acid oxidation capacity. SCENITH is the best technology to analyze and deepen our knowledge in the metabolism field, specially for rare but important immune cells types
Lopes, N., McIntyre, C., Martin, S. et al. Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments.
Nat Immunol (2021). https://doi.org/10.1038/s41590-020-00848-3